Funded scientist among #NobelPrize winners in #Physiology or #Medicine

Gregg Semenza

Gregg Semenza

Their discoveries have also provided promising strategies for combatting anaemia, cancer and other diseases.

The Nobel Prize for Medicine announcement kicked off Nobel week.

The 2019 Nobel Prize in Physiology or Medicine was jointly awarded to two Americans and a British scientist on Monday for their discoveries of how cells sense and adapt to oxygen availability.

'The seminal discoveries by this year's Nobel Laureates revealed the mechanism for one of life's most essential adaptive processes. Semenza, on the other hand, missed the first pre-dawn call from the Swedish academy, and waited several anxious minutes by the phone, answering it second time around. Semenza and Ratcliffe dug into how this gene worked on a cellular level, with the former publishing breakthrough work on the subject 1995. Individuals who inherit this rare condition develop tumors that over produce the distress signal associated with hypoxia-making it a prime candidate to study the body's oxygen-regulation tools.

The three scientists didn't straight collaborate, but see each others' papers and met and shared ideas at conventions. By better understanding these pathways, scientists can devise drugs to fight disease.

In the event of somebody who had a heart attack, the thought is to spur EPO generation and thus raise the formation of blood cells and cells. China approved such a drug for anemia previous year.

"Here I am as a cancer biologist helping contribute to another medication for hematological illness, specifically nausea", he explained, adding he expected to use his voice to advocate for adequate funding for science. "We made the discoveries when we were young, but we get recognized when we're old", the 63-year-old director of the Vascular Research Program at the Johns Hopkins Institute for Cell Engineering added.

"After she died, he believed winning the Nobel" will just be overly bittersweet and it'd be too devastating" he stated,"but I am at a stage today where I'd like to believe she is grinning down and nodding and saying'I told you, I told you that this sometimes happens.

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